Hypertensive disease
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Structural equation modeling for hypertension and type 2 diabetes based on multiple SNPs and multiple phenotypes.
|
31513605 |
2019 |
Hypertensive disease
|
|
0.800 |
GeneticVariation
|
BEFREE |
Recently STK39 rs3754777, ATP2B1 rs2681472 and rs17249754 have been associated with BP variation and hypertension.
|
31242870 |
2019 |
Essential Hypertension
|
|
0.020 |
GeneticVariation
|
BEFREE |
Our results confirmed the significant association of ATP2B1 rs17249754 with the risk of developing EH in Burkinabe and showed an increase of cardiovascular risk markers levels in subjects with EH.
|
31242870 |
2019 |
Hypertensive disease
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Interethnic analyses of blood pressure loci in populations of East Asian and European descent.
|
30487518 |
2018 |
Mean blood pressure
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Interethnic analyses of blood pressure loci in populations of East Asian and European descent.
|
30487518 |
2018 |
Systolic Pressure
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Interethnic analyses of blood pressure loci in populations of East Asian and European descent.
|
30487518 |
2018 |
Diastolic blood pressure
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Interethnic analyses of blood pressure loci in populations of East Asian and European descent.
|
30487518 |
2018 |
Systolic Pressure
|
|
0.700 |
GeneticVariation
|
GWASCAT |
A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.
|
29455858 |
2018 |
Diastolic blood pressure
|
|
0.700 |
GeneticVariation
|
GWASCAT |
A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.
|
29455858 |
2018 |
Hypertensive disease
|
|
0.800 |
GeneticVariation
|
BEFREE |
In conclusion, people with the major allele of ATP2B1 rs17249754 are susceptible to hypertension especially in low intake of Ca and high ratio of Na and K.
|
28934190 |
2017 |
Diastolic blood pressure
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney.
|
28739976 |
2017 |
Systolic Pressure
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney.
|
28739976 |
2017 |
Systolic Pressure
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension.
|
27618447 |
2016 |
Hypertensive disease
|
|
0.800 |
GeneticVariation
|
BEFREE |
That is, carriers with ATP2B1 rs17249754 homozygote mutant allele may be at higher risk of hypertension, when they consume excessive sodium intake.
|
27149052 |
2016 |
Hypertensive disease
|
|
0.800 |
GeneticVariation
|
BEFREE |
The MDR analysis demonstrated that the interaction of rs2070759, rs17249754, TC, TG, and BMI increased the susceptibility to hypertension.
|
26933664 |
2016 |
Essential Hypertension
|
|
0.020 |
GeneticVariation
|
BEFREE |
Chi-squared test, logistic regression, and propensity score analysis showed that rs17249754 was associated with EHT, particularly in females.
|
26933664 |
2016 |
Mean blood pressure
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation.
|
26390057 |
2015 |
Systolic Pressure
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation.
|
26390057 |
2015 |
Diastolic blood pressure
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation.
|
26390057 |
2015 |
Hypertensive disease
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Genome-wide association study in Chinese identifies novel loci for blood pressure and hypertension.
|
25249183 |
2015 |
Systolic Pressure
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Genome-wide association study in Chinese identifies novel loci for blood pressure and hypertension.
|
25249183 |
2015 |
Diastolic blood pressure
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Genome-wide association study in Chinese identifies novel loci for blood pressure and hypertension.
|
25249183 |
2015 |
Hypertensive disease
|
|
0.800 |
GeneticVariation
|
BEFREE |
Five gene variants, rs11066280 (C12orf51), rs12229654 and rs3782889 (MYL2), rs2072134 (OAS3), rs2093395 (TREML2), and rs17249754 (ATP2B1), were found to be associated with hypertension mostly in men (P = 4.76 × 10(-14) to 4.46 × 10(-7) in the joint analysis); three SNPs (rs11066280, rs12229654, and rs3782889) remained significant after Bonferroni correction in an independent population.
|
24142389 |
2014 |
Hyperlipidemia
|
|
0.010 |
GeneticVariation
|
BEFREE |
Three gene variants, rs12229654, rs17249754, and rs11066280, were significantly associated with metabolic disorders such as hyperlipidemia and diabetes (P = 0.00071 to 0.0097, respectively).
|
24142389 |
2014 |
Diabetes
|
|
0.010 |
GeneticVariation
|
BEFREE |
Three gene variants, rs12229654, rs17249754, and rs11066280, were significantly associated with metabolic disorders such as hyperlipidemia and diabetes (P = 0.00071 to 0.0097, respectively).
|
24142389 |
2014 |